Asante Kotoko stretched their lead to nine points after brushing aside Wa All Stars 2-0 at the Baba Yara Stadium.
Striker Ben Acheampong shot ahead before Prince Baffoe connected a corner a Daniel Nii Adjei cross from the left back.
All Stars finished the game with ten men after defender Albert Gaise.
Kotoko’s rivals Hearts missed a penalty in their 0-0 draw with Tema Youth who ended the match with ten men.
Wassaman United moved from the foot of the table to beat Medeama SC 3-2 at the Tarkwa T&A Park.
New Edubiase United came from two goals down to 2-2 with Liberty Professionals at the Gyemfi Park in Bekwai.
Heart of Lions nicked a 1-0 win against defending champions Berekum Chelsea at the Kpando Park.
Edubiase 2-2 Liberty
Wassaman 3-2 Medeama
Arsenal 0-0 Bechem United
Heart of Lions 1-0 Berekum Chelsea
Hearts of Oak 0-0 Tema Youth
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