The six-time Ballon d'Or winner was unable to inspire Mauricio Pochettino's side to victory at Roazhon Park.
Lionel Messi suffered his first loss as a Paris Saint-Germain player as the Ligue 1 leaders failed to register a single shot on target in a 2-0 defeat at Rennes on Sunday.
Messi returned to PSG's starting XI after his match-winning turn in their 2-0 victory over Manchester City in the Champions League last week, during which he registered his first goal for the club since signing on a free transfer following his departure from Barcelona.
The 34-year-old was unable to have the same impact at Roazhon Park, with Rennes producing an impressive all-around performance to spring an upset and hand Mauricio Pochettino's side their first league defeat of the 2021-22 campaign.
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